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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
H2A1_HUMAN
USC-OGP 2-DE database
:
H2A1_HUMAN
H2A1_HUMAN
General information about the entry
View entry in simple text format
Entry name
H2A1_HUMAN
Primary accession number
P0C0S8
Secondary accession number(s)
P02261
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Histone H2A type 1; Short=H2A.1; AltName: Full=Histone H2A/p;.
Gene name
Name=HIST1H2AG
Synonyms=H2AFP
and
Name=HIST1H2AI
Synonyms=H2AFC
and
Name=HIST1H2AK
Synonyms=H2AFD
and
Name=HIST1H2AL
Synonyms=H2AFI
and
Name=HIST1H2AM
Synonyms=H2AFN
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1333
:
pI=4.59; Mw=16158
SPOT OGP-1335
:
pI=5.02; Mw=16085
SPOT OGP-1336
:
pI=5.13; Mw=15865
SPOT OGP-1338
:
pI=5.68; Mw=15649
Cross-references
UniProtKB/Swiss-Prot
P0C0S8; H2A1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
H2A1_HUMAN
Primary accession number
P0C0S8
Secondary accession number(s)
P02261 Q2M1R2 Q76PA6
Sequence was last modified on
January 23, 2007 (version 2)
Annotations were last modified on
March 15, 2017 (version 126)
Name and origin of the protein
Description
RecName: Full=Histone H2A type 1; Short=H2A.1; AltName: Full=Histone H2A/p;
Gene name
Name=HIST1H2AG
Synonyms=H2AFP
and
Name=HIST1H2AI
Synonyms=H2AFC
and
Name=HIST1H2AK
Synonyms=H2AFD
and
Name=HIST1H2AL
Synonyms=H2AFI
and
Name=HIST1H2AM
Synonyms=H2AFN
Encoded on
Name=HIST1H2AG; Synonyms=H2AFP; and Name=HIST1H2AI; Synonyms=H2AFC; and Name=HIST1H2AK; Synonyms=H2AFD; and Name=HIST1H2AL; Synonyms=H2AFI; and Name=HIST1H2AM; Synonyms=H2AFN
Keywords
3D-structure
;
Acetylation
;
Chromosome
;
Citrullination
;
Complete proteome
;
DNA-binding
;
Isopeptide bond
;
Methylation
;
Nucleosome core
;
Nucleus
;
Phosphoprotein
;
Reference proteome
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
Z83742; CAB06037.1
; -; Genomic_DNA
EMBL
Z83739; CAB06034.1
; -; Genomic_DNA
EMBL
X83549; CAA58539.1
; -; Genomic_DNA
EMBL
X57138; CAA40417.1
; -; Genomic_DNA
EMBL
L19778; AAC24466.1
; -; mRNA
EMBL
AY131987; AAN59968.1
; -; Genomic_DNA
EMBL
AY131989; AAN59970.1
; -; Genomic_DNA
EMBL
AY131991; AAN59972.1
; -; Genomic_DNA
EMBL
AY131992; AAN59973.1
; -; Genomic_DNA
EMBL
AY131993; AAN59974.1
; -; Genomic_DNA
EMBL
Z98744; CAB11417.1
; -; Genomic_DNA
EMBL
Z98744; CAD24073.1
; -; Genomic_DNA
EMBL
Z98744; CAD24077.1
; -; Genomic_DNA
EMBL
AL009179; CAA15669.1
; -; Genomic_DNA
EMBL
AL021807; CAA16948.1
; -; Genomic_DNA
EMBL
BC016677; AAH16677.1
; -; mRNA
EMBL
BC069306; AAH69306.1
; -; mRNA
EMBL
BC104199; AAI04200.1
; -; mRNA
EMBL
BC104198; AAI04199.1
; -; mRNA
EMBL
BC105129; AAI05130.1
; -; mRNA
EMBL
BC112072; AAI12073.1
; -; mRNA
EMBL
BC112254; AAI12255.1
; -; mRNA
EMBL
BC112256; AAI12257.1
; -; mRNA
CCDS
CCDS4619.1; -
; .
CCDS
CCDS4626.1; -
; .
CCDS
CCDS4632.1; -
; .
CCDS
CCDS4634.1; -
; .
CCDS
CCDS4639.1; -
; .
PIR
B56624; HSHUA1
; .
RefSeq
NP_003500.1; NM_003509.2
; .
RefSeq
NP_003501.1; NM_003510.2
; .
RefSeq
NP_003502.1; NM_003511.2
; .
RefSeq
NP_003505.1; NM_003514.2
; .
RefSeq
NP_066408.1; NM_021064.4
; .
UniGene
Hs.134999; -
; .
UniGene
Hs.233568; -
; .
UniGene
Hs.51011; -
; .
UniGene
Hs.534035; -
; .
UniGene
Hs.734717; -
; .
PDB
4QYL; X-ray
; 1.80 A; E/F/G/H=2-13
PDB
5KGF; EM
; 4.54 A; C/G=1-130
PDBsum
4QYL; -
; .
PDBsum
5KGF; -
; .
ProteinModelPortal
P0C0S8; -
; .
SMR
P0C0S8; -
; .
BioGrid
113925; 10
; .
BioGrid
113926; 12
; .
BioGrid
113928; 10
; .
BioGrid
113932; 12
; .
BioGrid
114459; 39
; .
DIP
DIP-39638N; -
; .
IntAct
P0C0S8; 22
; .
MINT
MINT-1519720; -
; .
STRING
9606.ENSP00000352627; -
; .
iPTMnet
P0C0S8; -
; .
PhosphoSitePlus
P0C0S8; -
; .
SwissPalm
P0C0S8; -
; .
BioMuta
HIST1H2AG; -
; .
DMDM
83288406; -
; .
EPD
P0C0S8; -
; .
MaxQB
P0C0S8; -
; .
PaxDb
P0C0S8; -
; .
PeptideAtlas
P0C0S8; -
; .
PRIDE
P0C0S8; -
; .
TopDownProteomics
P0C0S8; -
; .
DNASU
8329; -
; .
DNASU
8330; -
; .
DNASU
8332; -
; .
DNASU
8969; -
; .
Ensembl
ENST00000358739; ENSP00000351589
; ENSG00000196747; .
Ensembl
ENST00000359193; ENSP00000352119
; ENSG00000196787; .
Ensembl
ENST00000359611; ENSP00000352627
; ENSG00000278677; .
Ensembl
ENST00000613174; ENSP00000482538
; ENSG00000276903; .
Ensembl
ENST00000618958; ENSP00000482431
; ENSG00000275221; .
GeneID
8329; -
; .
GeneID
8330; -
; .
GeneID
8332; -
; .
GeneID
8336; -
; .
GeneID
8969; -
; .
KEGG
hsa:8329; -
; .
KEGG
hsa:8330; -
; .
KEGG
hsa:8332; -
; .
KEGG
hsa:8336; -
; .
KEGG
hsa:8969; -
; .
UCSC
uc003niw.4; human
; .
CTD
8329; -
; .
CTD
8330; -
; .
CTD
8332; -
; .
CTD
8336; -
; .
CTD
8969; -
; .
DisGeNET
8332; -
; .
DisGeNET
8969; -
; .
GeneCards
HIST1H2AG; -
; .
GeneCards
HIST1H2AI; -
; .
GeneCards
HIST1H2AK; -
; .
GeneCards
HIST1H2AL; -
; .
GeneCards
HIST1H2AM; -
; .
H-InvDB
HIX0200889; -
; .
HGNC
HGNC:4737; HIST1H2AG
; .
HGNC
HGNC:4725; HIST1H2AI
; .
HGNC
HGNC:4726; HIST1H2AK
; .
HGNC
HGNC:4730; HIST1H2AL
; .
HGNC
HGNC:4735; HIST1H2AM
; .
HPA
HPA041189; -
; .
MIM
602787; gene
; .
MIM
602788; gene
; .
MIM
602793; gene
; .
MIM
602796; gene
; .
MIM
615012; gene
; .
neXtProt
NX_P0C0S8; -
; .
OpenTargets
ENSG00000196747; -
; .
OpenTargets
ENSG00000196787; -
; .
OpenTargets
ENSG00000275221; -
; .
OpenTargets
ENSG00000276903; -
; .
OpenTargets
ENSG00000278677; -
; .
PharmGKB
PA29114; -
; .
eggNOG
KOG1756; Eukaryota
; .
eggNOG
COG5262; LUCA
; .
GeneTree
ENSGT00760000118934; -
; .
GeneTree
ENSGT00860000133717; -
; .
GeneTree
ENSGT00870000136488; -
; .
HOGENOM
HOG000234652; -
; .
HOVERGEN
HBG009342; -
; .
InParanoid
P0C0S8; -
; .
KO
K11251; -
; .
OMA
GRIVPRH; -
; .
OrthoDB
EOG091G0XGD; -
; .
PhylomeDB
P0C0S8; -
; .
TreeFam
TF300137; -
; .
Reactome
R-HSA-3214815; HDACs deacetylate histones
; .
Reactome
R-HSA-3214847; HATs acetylate histones
; .
Reactome
R-HSA-3214858; RMTs methylate histone arginines
; .
Reactome
R-HSA-5689603; UCH proteinases
; .
Reactome
R-HSA-5689880; Ub-specific processing proteases
; .
Reactome
R-HSA-5689901; Metalloprotease DUBs
; .
SIGNOR
P0C0S8; -
; .
ChiTaRS
HIST1H2AM; human
; .
GeneWiki
HIST1H2AG; -
; .
GeneWiki
HIST1H2AI; -
; .
GeneWiki
HIST1H2AK; -
; .
GeneWiki
HIST1H2AL; -
; .
GeneWiki
HIST1H2AM; -
; .
Proteomes
UP000005640; Chromosome 6
; .
Bgee
ENSG00000184348; -
; .
CleanEx
HS_HIST1H2AG; -
; .
CleanEx
HS_HIST1H2AI; -
; .
CleanEx
HS_HIST1H2AK; -
; .
CleanEx
HS_HIST1H2AL; -
; .
CleanEx
HS_HIST1H2AM; -
; .
ExpressionAtlas
P0C0S8; baseline and differential
; .
Genevisible
P0C0S8; HS
; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0000790; C:nuclear chromatin
; IBA:GO_Central; .
GO
GO:0000786; C:nucleosome
; IEA:UniProtKB-KW; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0003677; F:DNA binding
; IBA:GO_Central; .
GO
GO:0019899; F:enzyme binding
; IPI:UniProtKB; .
GO
GO:0006342; P:chromatin silencing
; IBA:GO_Central; .
Gene3D
1.10.20.10; -
; 1; .
InterPro
IPR009072; Histone-fold
; .
InterPro
IPR002119; Histone_H2A
; .
InterPro
IPR007125; Histone_H2A/H2B/H3
; .
InterPro
IPR032454; Histone_H2A_C
; .
InterPro
IPR032458; Histone_H2A_CS
; .
Pfam
PF00125; Histone
; 1; .
Pfam
PF16211; Histone_H2A_C
; 1; .
PRINTS
PR00620; HISTONEH2A
; .
SMART
SM00414; H2A
; 1; .
SUPFAM
SSF47113; SSF47113
; 1; .
PROSITE
PS00046; HISTONE_H2A
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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